Native Proteins and Derivatives
Abcam Native Human Ceruloplasmin protein, 1MG
Native Human Ceruloplasmin protein is a Human Full Length protein, expressed in Mammalian, with >=95% purity and suitable for SDS-PAGE.
Protein/ Peptide/ Enzyme Synonyms: Ceruloplasmin, Cuproxidase ceruloplasmin, Ferroxidase ceruloplasmin, Glutathione peroxidase ceruloplasmin, Glutathione-dependent peroxiredoxin ceruloplasmin, CP
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
ILEX LIFE SCIENCES LLC HUMAN THROMBIN PROTEIN 1 MG
Ilex Life Sciences Thrombin Human, Purified Protein (Plasma), 1 mg. CAS REGISTRY NO.: 9002-04-4. BIOLOGICAL ACTIVITY: The specific activity was found to be 2435 NIH Units/mg (NOTE: may vary with each lot number, please refer to the datasheet enclosed with your product). FORMULATION: Sterile filtered liquid solution; contains 0.15M NaCl, 0.1M Tris, pH 7.4. APPLICATION: As a result of its high proteolytic specificity, thrombin has become an important biochemical protein. The thrombin cleavage site (Leu-Val-Pro-Arg-Gly-Ser) is widely used in linker regions of recombinant fusion protein constructs. After the purification of the fusion protein, thrombin is used to cleave between the Arginine and Glycine residues of the cleavage site, efficiently removing the purification tag from the protein of interest with a high degree of specificity. OTHER NAMES: Native Activated Factor IIa, Factor 2A, F2, PT, RPRGL2, THPH1, coagulation factor II, EC 3.4.21.5, UniProtKB# P00734.
ILEX LIFE SCIENCES LLC PORCINE THROMBIN PROTEIN 1 KU
Ilex Life Sciences Thrombin Porcine, Purified Protein (1000 U). DESCRIPTION: Thrombin Porcine, purified native enzyme, lyophilized. CAS REGISTRY NO.: 9002-04-4. FORMULATION: Sterile filtered white lyophilized (freeze-dried) powder. Lyophilized powder from glycine, calcium chloride pH 7.0 containing 0.9% NaCl. OTHER NAMES: Native thrombin protein, Porcine Activated Factor IIa, Factor 2A, F2, PT, RPRGL2, THPH1, coagulation factor II, EC 3.4.21.5, UniProtKB# P00735. APPLICATION: As a result of its high proteolytic specificity, thrombin has become an important biochemical protein. The thrombin cleavage site (Leu-Val-Pro-Arg-Gly-Ser) is widely used in linker regions of recombinant fusion protein constructs. After the purification of the fusion protein, thrombin is used to cleave between the Arginine and Glycine residues of the cleavage site, efficiently removing the purification tag from the protein of interest with a high degree of specificity.
ILEX LIFE SCIENCES LLC BOVINE THROMBIN PROTEIN 2000 U
Ilex Life Sciences Thrombin Bovine, Purified Protein (2000 U). DESCRIPTION: Thrombin Bovine, purified native enzyme, lyophilized. CAS REGISTRY NO.: 9002-04-4. BIOLOGICAL ACTIVITY: 164 US units/mg protein (may vary with each lot number, please refer to enclosed datasheet). FORMULATION: Sterile filtered beige lyophilized powder; formulated with glycine, CaCl2 and sodium chloride, PH 6.8. APPLICATION: As a result of its high proteolytic specificity, thrombin has become an important biochemical protein. The thrombin cleavage site (Leu-Val-Pro-Arg-Gly-Ser) is widely used in linker regions of recombinant fusion protein constructs. After the purification of the fusion protein, thrombin is used to cleave between the Arginine and Glycine residues of the cleavage site, efficiently removing the purification tag from the protein of interest with a high degree of specificity. SYNONYMS: Activated Factor IIa, Factor 2A, F2, PT, RPRGL2, THPH1, coagulation factor II, EC 3.4.21.5, UniProtKB# P00735.
Sigma Aldrich Fine Chemicals Biosciences fibronectin fITC suitable
fibronectin is purified from human plasma (Cat. No. f0895). The protein is modified to contain covalently linked fluorescein 5-isothiocyanate (Cat. No. f7250).fibronectin also known as Cold-insoluble globulin is a large glycoprotein of the extracellular matrix that is coded by fN1 gene. It is expressed in the plasma and at the cell surface. fibronectin is a ubiquitous and essential component of the extracellular matrix (ECM) and plays a vital role during tissue repair. fibronectin functions both as a regulator of cellular processes and an important scaffolding protein to maintain and direct tissue organization and ECM composition. fibronectin plays an important role in cell adhesion and spreading and affect the routes of cell migration both in vivo and in culture. Proteolytic degradation of extracellular matrix (ECM) is a critical step during cell invasion and tissue transmigration that is required for many physiological and pathological processes. Cellular structures that mediate ce
Cayman Chemical Nat-20 S-yn 10mg
A TLR3 TLR8 and TLR9 receptor agonist selectively induces NF-KB activation in HEK293 cells expressing recombinant human TLR3 TLR8 or TLR9 (EC50s 4.8 13.45 and 5.66 UM respectively) over HEK293 cells expressing recombinant human TLR2 TLR4 TLR5 or TLR7 (EC50s >100 UM for all) induces TNF-a IL-6 and IL-8 production in THP-1 cells from 5-40 UM inhibits the growth of HeLa cells (IC50 2.71 UM)
Sigma Aldrich Fine Chemicals Biosciences Lipoprotein Lipase from Ps10MG
Lipoprotein Lipase (LPL) is majorly secreted by myocytes and adipocytes in humans and is crucial for triglyceride homeostatis. Mutations in the catalytic domain of LPL impairs its interaction with glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 (GPIHBP1). The N-terminal catalytic domain is essential for lipolysis. The C-terminal is crucial for binding lipoproteins. Altered LPL levels may play role in the pathogenesis of atherosclerosis coronary heart disease and chronic lymphocytic leukemia.
Sigma Aldrich Fine Chemicals Biosciences Cas9 Protein from AStrepto
Recombinant Cas9 protein from Streptococcus pyogenes (~160 KD) is a ready-to-use reagent for genome engineering experiments. When combined with target-specific guide RNAs wild type Streptococcus pyogenes Cas9 protein will act as a targeted nuclease suitable for transfection of cell cultures and for the accelerated development of genetically-modified animals via one-cell embryo injection.
Sigma Aldrich Fine Chemicals Biosciences Tissue plasminogen activat
Tissue plasminogen activator (tPA) is a protease of the S1 family (trypsin family) and is found in a wide variety of mammalian tissues especially endothelial cells. tPA is secreted as a single chain precursor which is cleaved to a two-chain form by plasmin. Supplied in the single chain form with a molecular weight of ~70nbspkDa. The Tissue Plasminogen Activator (tPA) gene is mapped to human chromosome 8p11.21 and encodes a protease of 69nbspkDa majorly containing serine amino acid residue. It is predominantly expressed in endothelial cells.
Cayman Chemical 11mthyl LaurIc ACD mthyl 20mg
An a2-AR agonist binds to a2-AR in calf cortex rat kidney and rat spleen (IC50s 0.9 4.3 and 4.2 nM respectively) binds to a2-AR in rat cerebral cortex membrane pig submandibular gland and lung tissue and dog kidney membrane (Kds 0.87 5.28 1.30 and 5.25 nM respectively) inhibits noradrenaline-stimulated contraction in guinea pig ileum and rabbit vas deferens (EC50s 7.59 and 6.76 nM respectively)
Abcam Assay Kits, Enzyme substrates, Enzyme substrates for Peptidases, Enzyme substrates for Proteases, Magic RedTM-(FR)2 Cathepsin B Assay Kit - 25tests, Magic Red substrate-based assays are designed to detect Cathepsin protease activity within whole living cells, 1 kit
Assay Kits, Enzyme substrates, Enzyme substrates for Peptidases, Enzyme substrates for Proteases, Magic RedTM-(FR)2 Cathepsin B Assay Kit - 25tests, Magic Red substrate-based assays are designed to detect Cathepsin protease activity within whole living cells, 1 kit
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical RpGunosIn5O 1thIotrIp 2.7mg
An aldose reductase inhibitor (IC50 28.9 pM) reduces infarct area in streptozotocin-induced diabetic mice expressing human aldose reductase in a model of cardiomyopathy induced by ischemia-reperfusion injury at 40 mg/kg
Cayman Chemical SARSCoV2 NucleocapsId Prote
An activator of Nrf2 signaling increases the expression of Nrf2 target genes and activates HO-1 in CV-1 cells at 100 nM binds to PPARY and PPARa (Kis 344 and 232 nM respectively) and induces PPARY transactivation in SW480 cells inhibits NOS production in isolated mouse macrophages (IC50 0.014 nM) inhibits proliferation of U937 and MCF-7 cells at 300 nM reduces fatty acid synthesis in LiSa-2 human liposarcoma cells at 100 nM reduces tumor growth in a B16 murine melanoma model at 50 Ug/animal twice per day
Cayman Chemical ClusterIn MoncLNalCLN 9 100uL
An inhibitor of cardiac myosin ATPase (IC50 1.26 UM for the bovine enzyme) reduces fractional shortening in isolated rat cardiac ventricular myocytes (IC50 7.9 UM) as well as in rats in a dose-dependent manner
Cayman Chemical Dansyl Amde 1g
An internal standard for the quantification of gemfibrozil by GC- or LC-MS